Enabling a brand to move from a later- to earlier line of therapy for a highly prevalent chronic disease

A biopharma company with an established brand wanted to shift its market positioning from predominantly late-line therapy to earlier lines of therapy in a large primary care market, navigating generic competition in first-line therapy and needing to identify high-value HCPs from a large pool. It used Definitive Healthcare's AI/ML algorithms within its advanced analytics offering to analyze longitudinal patient data, segment the market by patient/physician/payor characteristics, and predict optimal timing for physicians to migrate patients from generic to branded therapy while accounting for comorbidities. The brand saw a 215% increase in movement from later- to earlier-line therapy and 80% growth in total patient population across all lines over two years, becoming established as a first-line therapy, "replacing generics."

The customer is anonymised in Definitive Healthcare’s own case study — not withheld by us.

Definitive Healthcare is a claims and provider-reference data platform used by pharma commercial teams for go-to-market planning and sales targeting.

This sits in the Data Providers stage of the AI use-case lifecycle: Named examples from the real-world-data, claims and competitive-intelligence providers pharma AI systems are trained on, benchmarked against, or run inside of.