External Control Arms Overview

The page explains that an external control arm uses real-world data (RWD) to describe how a disease progresses in a population not receiving the experimental drug, which is especially useful for single-arm trials where a traditional control group is infeasible or unethical. It offers a downloadable case study illustrating how Datavant enables external control arms using an oncology example. The visible page content does not include the specific numerical details of that oncology case -- it functions mainly as an overview/gateway to the downloadable material.

The customer is anonymised in Datavant’s own case study — not withheld by us.

Datavant is the tokenization and linkage infrastructure behind most of the US real-world-data ecosystem — it de-identifies and connects patient records across health-data partners without exposing PII.

This sits in the Data Providers stage of the AI use-case lifecycle: Named examples from the real-world-data, claims and competitive-intelligence providers pharma AI systems are trained on, benchmarked against, or run inside of.