J&J built a closed-loop digital process twin for solvent switching in active ingredient production.
Solvent-switch steps consumed too much time and resource when scaling from lab to commercial production at the Beerse and Geel sites. Siemens built a digital process twin on gPROMS FormulatedProducts and the gPROMS Digital Applications Platform, calibrated with plant data and linked to SIPAT. The page states solvent consumption down 30%, switch time down 35% and total costs down 35%.
Siemens is an industrial technology group whose Opcenter MES, automation and digital twin software are used across pharma production and process development
This sits in the Build stage of the AI use-case lifecycle: Named examples from the foundation-model labs and platforms pharma teams use to actually construct, train and generate the model or application.
Published by Siemens on its own site — read the original case study on siemens.com ↗
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